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. 1976 Jan;125(1):382-4.
doi: 10.1128/jb.125.1.382-384.1976.

Increased loss of duplicated genes in streptomycin-resistant (strA) mutants of Escherichia coli k-12

M H Simonian, R D Mosteller

Increased loss of duplicated genes in streptomycin-resistant (strA) mutants of Escherichia coli k-12

M H Simonian et al. J Bacteriol. 1976 Jan.

Abstract

The recombination-dependent loss of a duplicated portion of the Escherichia coli chromosome is five- to tenfold greater in strains containing streptomycin resistance (strA) mutations than in the strA+ parental strain. Streptomycin (500 mug/ml) partially reverses the increase. These results suggest an interaction between strA mutations and recombination.

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