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. 2000 Oct;63(10):1369-72.
doi: 10.1021/np000115g.

Three new scalarane sesterterpenoids from the Okinawan sponge Hyrtios erectus

H Miyaoka  1 , S Nishijima, H Mitome, Y Yamada
Affiliations

Three new scalarane sesterterpenoids from the Okinawan sponge Hyrtios erectus

H Miyaoka et al. J Nat Prod. 2000 Oct.

Abstract

Three new scalarane sesterterpenoids-hyrtiolide (1), 16-hydroxyscalarolide (2), and 12-deacetyl-Delta(17)-hyrtial (3), were isolated from Okinawan sponge Hyrtios erectus, along with scalarolide (4) and 12-deacetylhyrtial (5). The structures of new compounds 1-3 were determined by spectroscopic analysis and chemical conversions. Compounds 3 and 5 showed antiproliferative activity toward KB cells.

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