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. 1976 Jan;73(1):198-202.
doi: 10.1073/pnas.73.1.198.

Novel F prime factors able to replicate in Escherichia coli Hfr strains

S Hiraga

Novel F prime factors able to replicate in Escherichia coli Hfr strains

S Hiraga. Proc Natl Acad Sci U S A. 1976 Jan.

Abstract

A novel type of F' plasmid that can replicate extrachromosomally in cells of Hfr strains has been isolated. Genetic analysis of these plasmids indicates that all carry the dnaA-bglA region of the E. coli chromosome as well as ilv+ used as a selective marker. It is suggested that a specific site, designated poh+ (permissive on Hfr), is located in this region, and is essential for these plasmids to replicate in Hfr cells. The most interesting explanation, among others, would be that the poh+ site represents the replication origin of the bacterial chromosome.

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References

    1. J Bacteriol. 1975 Mar;121(3):1007-13 - PubMed
    1. J Bacteriol. 1967 Jan;93(1):264-72 - PubMed
    1. Mol Gen Genet. 1975;137(3):249-61 - PubMed
    1. Mol Gen Genet. 1975;137(3):239-48 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 Jan;59(1):285-92 - PubMed

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