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Review
. 2000 Nov;21(11):573-83.
doi: 10.1016/s0167-5699(00)01735-7.

NKT cells: facts, functions and fallacies

D I Godfrey  1 , K J Hammond, L D Poulton, M J Smyth, A G Baxter
Affiliations
Review

NKT cells: facts, functions and fallacies

D I Godfrey et al. Immunol Today. 2000 Nov.

Abstract

The proposed roles of NK1.1(+) T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function. This review aims to provide an update on NKT cell biology and, whenever possible, to compare what is known about NKT-cell subsets.

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