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. 1999 Aug;1(3):279-288.
doi: 10.1007/s11908-999-0031-5.

Human Herpesvirus 8 Infections

RM Greenblatt  1
Affiliations

Human Herpesvirus 8 Infections

RM Greenblatt. Curr Infect Dis Rep. 1999 Aug.

Abstract

Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma (KS)-associated herpesvirus is a recently identified virus that is associated with KS, multicentric Castleman's disease, and body cavity-based lymphomas. KS is the most common kind of cancer in AIDS patients and the initial AIDS-defining condition in over 20% of patients. HHV-8 DNA has now been detected in over 95% of KS tissue samples supporting the concept that HHV-8 has a causal role in KS. The discovery has opened new avenues for understanding the epidemiology, pathogenesis, and treatment of KS and related conditions.

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