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. 2000 Dec;107(12):2233-9.
doi: 10.1016/s0161-6420(00)00417-6.

Surgical repair of full-thickness idiopathic macular holes associated with significant macular drusen

D M Berinstein  1 , T S Hassan, G A Williams, R R Margherio, A J Ruby, B R Garretson
Affiliations

Surgical repair of full-thickness idiopathic macular holes associated with significant macular drusen

D M Berinstein et al. Ophthalmology. 2000 Dec.

Abstract

Objective: To evaluate the visual and anatomic results of surgically repaired macular holes in eyes with intermediate or large-sized macular drusen.

Design: Retrospective noncomparative case series.

Participants: Thirty-four eyes of 32 patients undergoing macular hole surgery with preoperative intermediate or large-sized macular drusen as defined by the Age-Related Eye Disease Study (AREDS).

Intervention: Pars plana vitrectomy for standard macular hole repair performed by multiple surgeons.

Main outcome measures: Visual acuity, anatomic hole closure.

Results: Initial hole closure failed in 8 eyes (24%) overall, 5 of 28 eyes (18%) with AREDS category 2 drusen and 3 of 6 eyes (50%) with category 3 drusen (P = 0.1263). Final macular hole closure was seen in 93% of category 2 and 67% of category 3 eyes (P = 0.1347). Mean final visual acuity was 20/60 overall, 20/60 for category 2, and 20/50 for category 3 eyes.

Conclusions: A trend of reduced initial macular hole closure was seen in eyes with significant macular drusen. Reoperation improved closure rates. If closure was accomplished, visual outcomes were excellent.

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  • Surgery for full-thickness macular holes.
    Aras C, Unal M, Yolar M, Arvas S, Yetik H, Akar S, Muftuoglu G, Guzel H, Ozkan S. Aras C, et al. Ophthalmology. 2001 Dec;108(12):2156-7. doi: 10.1016/s0161-6420(01)00871-5. Ophthalmology. 2001. PMID: 11733243 No abstract available.

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