The role of different subsets of T regulatory cells in controlling autoimmunity
- PMID: 11102772
- DOI: 10.1016/s0952-7915(00)00162-x
The role of different subsets of T regulatory cells in controlling autoimmunity
Abstract
T regulatory cells-in addition to clonal deletion and anergy-are essential for the downregulation of T cell responses to both foreign and self antigens, and for the prevention of autoimmunity. Recent progress has been made in characterising the different subsets of T regulatory cells, the factors that drive their differentiation, and their mode of action. The resolution of these mechanisms will make it possible to use T regulatory cells therapeutically in human autoimmune diseases.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources