Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2000 Nov:7 Suppl:982-5.
doi: 10.1038/80768.

Protein NMR spectroscopy in structural genomics

Affiliations
Review

Protein NMR spectroscopy in structural genomics

G T Montelione et al. Nat Struct Biol. 2000 Nov.

Abstract

Protein NMR spectroscopy provides an important complement to X-ray crystallography for structural genomics, both for determining three-dimensional protein structures and in characterizing their biochemical and biophysical functions.

PubMed Disclaimer

Similar articles

Cited by

  • Solution NMR structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii.
    Aramini JM, Huang YJ, Cort JR, Goldsmith-Fischman S, Xiao R, Shih LY, Ho CK, Liu J, Rost B, Honig B, Kennedy MA, Acton TB, Montelione GT. Aramini JM, et al. Protein Sci. 2003 Dec;12(12):2823-30. doi: 10.1110/ps.03359003. Protein Sci. 2003. PMID: 14627742 Free PMC article.
  • Protein production and purification.
    Structural Genomics Consortium; China Structural Genomics Consortium; Northeast Structural Genomics Consortium; Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schütz A, Heinemann U, Yokoyama S, Büssow K, Gunsalus KC. Structural Genomics Consortium, et al. Nat Methods. 2008 Feb;5(2):135-46. doi: 10.1038/nmeth.f.202. Nat Methods. 2008. PMID: 18235434 Free PMC article. Review.
  • Fully automated high-quality NMR structure determination of small (2)H-enriched proteins.
    Tang Y, Schneider WM, Shen Y, Raman S, Inouye M, Baker D, Roth MJ, Montelione GT. Tang Y, et al. J Struct Funct Genomics. 2010 Dec;11(4):223-32. doi: 10.1007/s10969-010-9095-6. Epub 2010 Aug 24. J Struct Funct Genomics. 2010. PMID: 20734145 Free PMC article.
  • POTENCI: prediction of temperature, neighbor and pH-corrected chemical shifts for intrinsically disordered proteins.
    Nielsen JT, Mulder FAA. Nielsen JT, et al. J Biomol NMR. 2018 Mar;70(3):141-165. doi: 10.1007/s10858-018-0166-5. Epub 2018 Feb 5. J Biomol NMR. 2018. PMID: 29399725
  • NMR in structural genomics to increase structural coverage of the protein universe: Delivered by Prof. Kurt Wüthrich on 7 July 2013 at the 38th FEBS Congress in St. Petersburg, Russia.
    Serrano P, Dutta SK, Proudfoot A, Mohanty B, Susac L, Martin B, Geralt M, Jaroszewski L, Godzik A, Elsliger M, Wilson IA, Wüthrich K. Serrano P, et al. FEBS J. 2016 Nov;283(21):3870-3881. doi: 10.1111/febs.13751. Epub 2016 Jun 9. FEBS J. 2016. PMID: 27154589 Free PMC article.

Publication types

LinkOut - more resources