Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2000 Dec 6;45(1):77-88.
doi: 10.1016/s0169-409x(00)00102-2.

Disposition characteristics of emulsions and incorporated drugs after systemic or local injection

S Kawakami  1 , F Yamashita, M Hashida
Affiliations
Review

Disposition characteristics of emulsions and incorporated drugs after systemic or local injection

S Kawakami et al. Adv Drug Deliv Rev. .

Abstract

Lipid emulsions are useful tools for controlling the in vivo disposition of drugs and plasmid DNA. The dispositions of lipid emulsions are determined by their tissue interaction depending on the anatomical and physiological characteristics of each tissue and the physicochemical and biological properties of lipid emulsions. In addition, the retention of drugs is another issue, as too rapid a release of the drug would lead to failure of exerting its therapeutic potency. This review presents an overview about the disposition profiles and various physicochemical properties of lipid emulsions and incorporated drugs after systemic or local injection. Controlled biodistribution of lipid emulsions and incorporated drugs are also discussed.

PubMed Disclaimer

Comment in

LinkOut - more resources