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Review
. 2000 Dec 8;87(12):1103-7.
doi: 10.1161/01.res.87.12.1103.

Ventricular fibrillation: how do we stop the waves from breaking?

J N Weiss  1 , P S Chen, Z Qu, H S Karagueuzian, A Garfinkel
Affiliations
Free article
Review

Ventricular fibrillation: how do we stop the waves from breaking?

J N Weiss et al. Circ Res. .
Free article

Abstract

Combined experimental and theoretical developments have demonstrated that in addition to preexisting electrophysiological heterogeneities, cardiac electrical restitution properties contribute to breakup of reentrant wavefronts during cardiac fibrillation. Developing therapies that favorably alter electrical restitution properties have promise as a new paradigm for preventing fibrillation.

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