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Comparative Study
. 2000;104(1):10-5.
doi: 10.1159/000041062.

Consequences of total and subtotal myeloperoxidase deficiency: risk or benefit ?

D Kutter  1 , P Devaquet, G Vanderstocken, J M Paulus, V Marchal, A Gothot
Affiliations
Comparative Study

Consequences of total and subtotal myeloperoxidase deficiency: risk or benefit ?

D Kutter et al. Acta Haematol. 2000.

Abstract

A group of 100 totally or subtotally myeloperoxidase (MPO)-deficient individuals was compared to a reference population of 118 probands selected at random. Data for a protective effect of the deficiency against cardiovascular damage are presented. On the other hand, a significantly higher occurrence of severe infections and chronic inflammatory processes was noted among the deficient patients. An increased incidence of cancer among the MPO-deficient individuals was not demonstrated.

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