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. 1976 Nov 15;32(11):1454-6.
doi: 10.1007/BF01937430.

Effects of morphine administration on cerebellar guanosine 3',5'-monophosphate

W E Askew, K D Charalampous

Effects of morphine administration on cerebellar guanosine 3',5'-monophosphate

W E Askew et al. Experientia. .

Abstract

An increase in mouse cerebellar C-GMP levels during acute morphine treatment was observed, which was possibly related to the decrease in C-GMP phosphodiesterase levels also observed in acute treatment. Chronic treatment lowered C-GMP levels as did abrupt withdrawal without naloxone.

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