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Review
. 2000 Dec;16(12):536-40.
doi: 10.1016/s0169-4758(00)01787-7.

Molecular crosstalk in host-parasite relationships: schistosome- and leech-host interactions

M Salzet  1 , A Capron, G B Stefano
Affiliations
Review

Molecular crosstalk in host-parasite relationships: schistosome- and leech-host interactions

M Salzet et al. Parasitol Today. 2000 Dec.

Abstract

The host-parasite relationship is based on subtle interplay between parasite survival strategies and host defense mechanisms. In this context, parasites often use the same or similar immune signaling molecules and/or molecular mimicry to escape host immunosurveillance. Both processes represent an adaptive strategy to ensure host immunocompatibility. This bidirectional communication between parasites and their hosts includes the renin-angiotensin, opioid and opiate systems. Here, Michel Salzet, André Capron and George Stefano review recent work on the interaction of common signaling mechanisms in schistosomes, leeches and their host.

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Comment in

  • Molecular mimicry in schistosomes.
    Thompson RC. Thompson RC. Trends Parasitol. 2001 Apr;17(4):168. doi: 10.1016/s1471-4922(01)01891-8. Trends Parasitol. 2001. PMID: 11360886 No abstract available.

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