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. 2001 Jan 1;29(1):49-51.
doi: 10.1093/nar/29.1.49.

The MetaFam Server: a comprehensive protein family resource

K A Silverstein  1 , E Shoop, J E Johnson, A Kilian, J L Freeman, T M Kunau, I A Awad, M Mayer, E F Retzel
Affiliations

The MetaFam Server: a comprehensive protein family resource

K A Silverstein et al. Nucleic Acids Res. .

Abstract

MetaFam is a comprehensive relational database of protein family information. This web-accessible resource integrates data from several primary sequence and secondary protein family databases. By pooling together the information from these disparate sources, MetaFam is able to provide the most complete protein family sets available. Users are able to explore the interrelationships among these primary and secondary databases using a powerful graphical visualization tool, MetaFamView. Additionally, users can identify corresponding sequence entries among the sequence databases, obtain a quick summary of corresponding families (and their sequence members) among the family databases, and even attempt to classify their own unassigned sequences. Hypertext links to the appropriate source databases are provided at every level of navigation. Global family database statistics and information are also provided. Public access to the data is available at http://metafam.ahc.umn.edu/.

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Figures

Figure 1
Figure 1
A snapshot of MetaFamView, the graphical visualization tool providing access to the database. The features of MetaFamView are briefly summarized in the text and demonstrated in the Supplementary Material.
See this image and copyright information in PMC

References

    1. Hofmann K., Bucher,P., Falquet,L. and Bairoch,A. (1999) The PROSITE database, its status in 1999. Nucleic Acids Res., 27, 215–219. - PMC - PubMed
    1. Gribskov M., McLachlan,A.D. and Eisenberg,D. (1987) Profile analysis: detection of distantly related proteins. Proc. Natl Acad. Sci. USA, 84, 4355–4358. - PMC - PubMed
    1. Henikoff J.G., Greene,E.A., Pietrokovski,S. and Henikoff,S. (2000) Increased coverage of protein families with the Blocks database servers. Nucleic Acids Res., 28, 228–230. - PMC - PubMed
    1. Attwood T.K., Croning,M.D.R., Flower,D.R., Lewis,A.P., Mabey,J.E., Scordis,P., Selley,J.N. and Wright,W. (2000) PRINTS-S: the database formerly known as PRINTS. Nucleic Acids Res., 28, 225–227. - PMC - PubMed
    1. Bateman A., Birney,E., Durbin,R., Eddy,S.R., Howe,K.L. and Sonnhammer,E.L.L. (2000) The Pfam protein families database. Nucleic Acids Res., 28, 263–266. - PMC - PubMed

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