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. 2001 Jan 1;29(1):98-101.
doi: 10.1093/nar/29.1.98.

The Mouse Gene Expression Database (GXD)

Affiliations

The Mouse Gene Expression Database (GXD)

M Ringwald et al. Nucleic Acids Res. .

Abstract

The Gene Expression Database (GXD) is a community resource of gene expression information for the laboratory mouse. By combining the different types of expression data, GXD aims to provide increasingly complete information about the expression profiles of genes in different mouse strains and mutants, thus enabling valuable insights into the molecular networks that underlie normal development and disease. GXD is integrated with the Mouse Genome Database (MGD). Extensive interconnections with sequence databases and with databases from other species, and the development and use of shared controlled vocabularies extend GXD's utility for the analysis of gene expression information. GXD is accessible through the Mouse Genome Informatics web site at http://www.informatics.jax.org/ or directly at http://www.informatics.jax.org/menus/expression_menu. shtml.

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Figures

Figure 1
Figure 1
The Mouse Anatomical Dictionary Browser. The hierarchy of anatomical structures may be entered by either browsing from the top level or by searching for specific terms. Searching for a term in the Anatomical Dictionary requires a text string and optional specification of Theiler stages to search (lower left panel). Results of the query (lower right panel) are sorted by stage and each structure is linked to a detail page. The detail page for an anatomical structure displays the structure’s name, synonyms and a view of the structure within the stage hierarchy (upper left panel). All superstructures, structures found at the same level as the selected structure and substructures are displayed. Each structure is linked to its own detail page. A plus sign next to a structure indicates that substructures exist. The number of expression results currently annotated to the selected structure is displayed next to the structure name. Clicking on this link retrieves expression assay result summaries (upper right panel) that lead to detailed expression data.

References

    1. Ringwald M., Baldock,R., Bard,J., Kaufman,M., Eppig,J.T., Richardson,J.E., Nadeau,J.H. and Davidson,D. (1994) A Database for Mouse Development. Science, 265, 2033–2034. - PubMed
    1. Ringwald M., Davis,G.L., Smith,A.G., Trepanier,L.E., Begley,D.A., Richardson,J.E. and Eppig,J.T. (1997) The Mouse Gene Expression Database GXD. Semin. Cell Dev. Biol., 8, 489–497. - PubMed
    1. Ringwald M., Mangan,M.E., Eppig,J.T., Kadin,J.A., Richardson,J.E. and the Gene Expression Database Group. (1999) GXD: a Gene Expression Database for the laboratory mouse. Nucleic Acids Res., 27, 106–112. - PMC - PubMed
    1. Ringwald M., Eppig,J.T., Kadin,J.A., Richardson,J.E. and the Gene Expression Database Group. (2000) GXD: a Gene Expression Database for the laboratory mouse: current status and recent enhancements. Nucleic Acids Res., 28, 115–119. - PMC - PubMed
    1. Ringwald M., Eppig,J.T. and Richardson,J.E. (2000) GXD: integrated access to gene expression data for the laboratory mouse. Trends Genet., 16, 188–190. - PubMed

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