Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2001 Jan 1;29(1):281-3.
doi: 10.1093/nar/29.1.281.

The TRANSFAC system on gene expression regulation

Affiliations

The TRANSFAC system on gene expression regulation

E Wingender et al. Nucleic Acids Res. .

Abstract

The TRANSFAC database on transcription factors and their DNA-binding sites and profiles (http://www.gene-regulation.de/) has been quantitatively extended and supplemented by a number of modules. These modules give information about pathologically relevant mutations in regulatory regions and transcription factor genes (PathoDB), scaffold/matrix attached regions (S/MARt DB), signal transduction (TRANSPATH) and gene expression sources (CYTOMER). Altogether, these distinct database modules constitute the TRANSFAC system. They are accompanied by a number of program routines for identifying potential transcription factor binding sites or for localizing individual components in the regulatory network of a cell.

PubMed Disclaimer

References

    1. Wingender E. (1988) Compilation of transcription regulating proteins. Nucleic Acids Res., 16, 1879–1902. - PMC - PubMed
    1. Wingender E., Heinemeyer,T. and Lincoln,D. (1991) Regulatory DNA sequences: predictability of their function. In Collins,J and Driesel,A.J. (eds), Genome Analysis – From Sequence to Function; BioTechForum – Advances in Molecular Genetics, 4, 95–108.
    1. Wingender E., Dietze,P., Karas,H. and Knüppel,R. (1996) TRANSFAC: A database on transcription factors and their DNA binding sites. Nucleic Acids Res., 24, 238–241. - PMC - PubMed
    1. Wingender E., Kel,A.E., Kel,O.V., Karas,H., Heinemeyer,T., Dietze,P., Knüppel,R., Romaschenko,A.G. and Kolchanov,N.A. (1997) TRANSFAC, TRRD and COMPEL: Towards a federated database system on transcriptional regulation. Nucleic Acids Res., 25, 265–268. - PMC - PubMed
    1. Heinemeyer T., Wingender,E., Reuter,I., Hermjakob,H., Kel,A.E., Kel,O.V., Ignatieva,E.V., Ananko,E.A., Podkolodnaya,O.A., Kolpakov,F.A., Podkolodny,N.L. and Kolchanov,N.A. (1998) Databases on Transcriptional Regulation: TRANSFAC, TRRD, and COMPEL. Nucleic Acids Res., 26, 362–367. - PMC - PubMed

Publication types