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. 2001 Jan 1;29(1):291-3.
doi: 10.1093/nar/29.1.291.

The Homeodomain Resource: sequences, structures, DNA binding sites and genomic information

S Banerjee-Basu  1 , D W Sink, A D Baxevanis
Affiliations

The Homeodomain Resource: sequences, structures, DNA binding sites and genomic information

S Banerjee-Basu et al. Nucleic Acids Res. .

Abstract

The Homeodomain Resource is an annotated collection of non-redundant protein sequences, three-dimensional structures and genomic information for the homeodomain protein family. Release 3.0 contains 795 full-length homeodomain-containing sequences, 32 experimentally-derived structures and 143 homeo-box loci implicated in human genetic disorders. Entries are fully hyperlinked to facilitate easy retrieval of the original records from source databases. A simple search engine with a graphical user interface is provided to query the component databases and assemble customized data sets. A new feature for this release is the addition of DNA recognition sites for all human homeodomain proteins described in the literature. The Homeodomain Resource is freely available through the World Wide Web at http://genome.nhgri.nih.gov/homeodomain.

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Figures

Figure 1
Figure 1
DNA binding sites for human homeodomain loci implicated in genetic or genomic disorders. Data is derived from the published literature, citations in OMIM, and entries for DNA-bound homeodomain structures from the Protein Data Bank. The core regions of each of the DNA binding sites are shown in bold type. An expanded version of this table is available online (at http://genome.nhgri.nih.gov/homeodomain); the expanded version includes a listing of alternative gene names, as well as citation information.
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