An ovarian Sertoli-Leydig cell tumour in a 40 year old Ethiopian woman: case report

Abstract

Sertoli-Leydig cell tumors of the ovary are uncommon ovarian tumors. They belong to the ovarian stromal neoplasm. The most striking mode of presentation of these tumours is virilization due to androgen secretion. But approximately 50% of patients with Sertoli-Leydig cell tumors have no endocrine manifestations and usually complain of abdominal pain or swelling. Occasional tumors have been associated with various estrogen syndromes. A forty year old Ethiopian lady with well differentiated Sertoli-Leydig cell tumor of the left ovary presenting with features of virilization is described with clinicopathological correlation and literature review.