Matrical inclusions induced by clofibrate in hepatic microbodies of rats fed 2-acetylaminofluorene
- PMID: 1113332
Item in Clipboard
Matrical inclusions induced by clofibrate in hepatic microbodies of rats fed 2-acetylaminofluorene
J Natl Cancer Inst.
1975 Feb.
Abstract
Abnormal inclusions in microbodies were induced by clofibrate in hepatocytes of hyperplastic liver nodules in rats fed 2-acetylaminofluorene. These were matrical tubules and plates, each with the same ultrastructural features as those reported previously by other investigators. A hyperplastic state of hepatocytes induced by hepatocarcinogens might be related to the formation of these inclusions in response to clofibrate.
Similar articles
-
Matrical inclusions of peroxisomes induced by clofibrate in preneoplastic hepatocytes of rats fed 3'-methyl-4-dimethyl-aminoazobenzene.Gan. 1982 Feb;73(1):7-13. Gan. 1982. PMID: 6288498
-
[Proceedings: Peroxisome in 2-fluorenylacetamide-induced hyperplastic liver nodule cells].Hokkaido Igaku Zasshi. 1975 Jan;50(1):78-9. Hokkaido Igaku Zasshi. 1975. PMID: 1171063 Japanese. No abstract available.
-
Changes in peroxisomes in preneoplastic liver of rats induced by 3'-methyl-4-dimethylaminoazobenzene.Cancer Res. 1977 Apr;37(4):1-35-43. Cancer Res. 1977. PMID: 191174
-
[Peroxisomes and hypolipidemic agents ].Sem Hop. 1982 Jul 8;58(28-29):1712-7. Sem Hop. 1982. PMID: 6289453 Review. French.
-
Hepatic and renal effects of peroxisome proliferators: biological implications.Ann N Y Acad Sci. 1982;386:81-110. doi: 10.1111/j.1749-6632.1982.tb21409.x. Ann N Y Acad Sci. 1982. PMID: 7046570 Review. No abstract available.
Cited by
-
Properties of peroxisomes and their induction by clofibrate in normal adult rat hepatocytes in primary culture.In Vitro. 1984 Jul;20(7):573-84. doi: 10.1007/BF02639773. In Vitro. 1984. PMID: 6469275