Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Feb;54(2):519-23.

Matrical inclusions induced by clofibrate in hepatic microbodies of rats fed 2-acetylaminofluorene

H Tsukada, Y Mochizuki, M Gotoh
  • PMID: 1113332

Matrical inclusions induced by clofibrate in hepatic microbodies of rats fed 2-acetylaminofluorene

H Tsukada et al. J Natl Cancer Inst. 1975 Feb.

Abstract

Abnormal inclusions in microbodies were induced by clofibrate in hepatocytes of hyperplastic liver nodules in rats fed 2-acetylaminofluorene. These were matrical tubules and plates, each with the same ultrastructural features as those reported previously by other investigators. A hyperplastic state of hepatocytes induced by hepatocarcinogens might be related to the formation of these inclusions in response to clofibrate.

PubMed Disclaimer

MeSH terms