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Clinical Trial
. 2001 Jan;178(1):36-41.
doi: 10.1192/bjp.178.1.36.

Evaluating the use of benzodiazepines following recent bereavement

J Warner  1 , C Metcalfe, M King
Affiliations
Clinical Trial

Evaluating the use of benzodiazepines following recent bereavement

J Warner et al. Br J Psychiatry. 2001 Jan.

Abstract

Background: There is no evidence to support current advice not to use benzodiazepines after bereavement.

Aims: To determine the role of benzodiazepines in the management of bereavement.

Method: We conducted a randomised, double-blind, placebo-controlled evaluation of the use of diazepam after recent bereavement. Participants were randomised to either 2 mg diazepam or identically packaged placebo up to three times daily. The primary outcome measure was the Bereavement Phenomenology Questionnaire.

Results: Thirty subjects were randomised. No evidence was found of an effect of benzodiazepines on the course of the first 6 months of bereavement (estimated mean difference of combined follow-up assessments=0.3 in favour of placebo; 95% Cl - 6.2 to +6.7).

Conclusion: We found no evidence of a positive or negative effect of benzodiazepines on the course of bereavement.

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