Review
doi: 10.1016/s0960-9822(00)00847-2.
X inactivation: Tsix and Xist as yin and yang
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- PMID: 11137025
- DOI: 10.1016/s0960-9822(00)00847-2
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Review
X inactivation: Tsix and Xist as yin and yang
Curr Biol.
2000 Dec.
Free article
Abstract
A new study shows that expression of Tsix, an antisense Xist gene, can be controlled by imprinting, and that high Tsix activity during X inactivation can protect the future active X chromosome from silencing by Xist. Tsix and Xist seem to have a yin and yang relationship, with opposite effects on X inactivation.
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