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Review
. 2000 Dec;10(24):R899-903.
doi: 10.1016/s0960-9822(00)00847-2.

X inactivation: Tsix and Xist as yin and yang

S K Mlynarczyk  1 , B Panning
Affiliations
Free article
Review

X inactivation: Tsix and Xist as yin and yang

S K Mlynarczyk et al. Curr Biol. 2000 Dec.
Free article

Abstract

A new study shows that expression of Tsix, an antisense Xist gene, can be controlled by imprinting, and that high Tsix activity during X inactivation can protect the future active X chromosome from silencing by Xist. Tsix and Xist seem to have a yin and yang relationship, with opposite effects on X inactivation.

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