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Review
. 2000 Dec;10(24):R919-22.
doi: 10.1016/s0960-9822(00)00852-6.

Wnt signaling: an embarrassment of receptors

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Free article
Review

Wnt signaling: an embarrassment of receptors

A Bejsovec. Curr Biol. 2000 Dec.
Free article

Abstract

Recent genetic studies in Drosophila and mouse have uncovered a new aspect of the Wnt signal transduction machinery. Mutations disrupting LDL-receptor related proteins produce loss-of-function Wnt phenotypes, suggesting that these cell surface molecules may represent essential co-receptors for Wnt ligands.

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