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Review
. 2001 Jan 6;322(7277):29-32.
doi: 10.1136/bmj.322.7277.29.

Islet and stem cell transplantation for treating diabetes

P Serup  1 , O D Madsen, T Mandrup-Poulsen
Affiliations
Review

Islet and stem cell transplantation for treating diabetes

P Serup et al. BMJ. .
No abstract available

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Figures

Figure 1
Figure 1
Islet cell transplantation by injection into hepatic portal vein
Figure 2
Figure 2
Schematic representation of developmental pathway an embryonic stem cell must follow in order to become an insulin producing β cell. Little is known about the signals that govern the choices at the various branch points
Figure 3
Figure 3
Therapeutic cloning (use of nuclear replacement to generate patient specific β cells). An enucleated host oocyte is injected with a nucleus derived from a somatic cell from a particular patient. The oocyte is then allowed to develop to the blastocyst stage in vitro. Embryonic stem cells can then be isolated from the blastocyst and used as the starting point for in vitro β cell development
See this image and copyright information in PMC

References

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    1. Ricordi C. Human islet cell transplantation: new perspectives for an old challenge. Diabetes Rev. 1996;4:356–369.
    1. Brendel M, Hering B, Schulz A, Bretzel R. International islet transplant registry. Giessen: Justus-Liebig University of Giessen; 1999. pp. 1–20.
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