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Review
. 2000 Dec;12(6):537-42.
doi: 10.1006/smim.2000.0276.

CD1d-restricted mouse V alpha 14 and human V alpha 24 T cells: lymphocytes of innate immunity

K Benlagha  1 , A Bendelac
Affiliations
Review

CD1d-restricted mouse V alpha 14 and human V alpha 24 T cells: lymphocytes of innate immunity

K Benlagha et al. Semin Immunol. 2000 Dec.

Abstract

Mouse V alpha 14 T cells and their human homologs, V alpha 24 T cells, are prominent subsets of CD1d-restricted T cells. Here we discuss their striking similarities to B-1 B cells and gammadelta T cells and propose that these immune cells mediate various innate strategies in response to endogenous or exogenous danger signals.

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