Review
doi: 10.1038/35050642.
Together until separin do us part
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- PMID: 11146641
- DOI: 10.1038/35050642
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Review
Together until separin do us part
Nat Cell Biol.
2001 Jan.
Abstract
Loss of sister-chromatid cohesion triggers chromosome segregation. Several recent reports show that the protease Esp1 cleaves the cohesin subunit Scc1/Mcd1 to induce sister-chromatid segregation in yeast and vertebrates. This finding indicates that cohesin cleavage may control sister-chromatid separation in all vertebrates.
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