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. 1999 Mar-Apr;75(3-4):17-20.

Immunological investigation of malaria and new perspectives in paleopathological studies

N Cerutti  1 , A Marin, E R Massa, D Savoia
Affiliations
  • PMID: 11148983

Immunological investigation of malaria and new perspectives in paleopathological studies

N Cerutti et al. Boll Soc Ital Biol Sper. 1999 Mar-Apr.

Abstract

We applied a paleoimmunological investigation, using an immunoenzymatic assay revealing trophozoite derived Plasmodium falciparum histidine rich protein-2 antigen (PfHRP-2). The investigation was carried out on skin, muscle and bone samples. We examined predynastic egyptian mummies (3200 B.C.) from Gebelen, belonging to the Marro's Collection of the Anthropological and Ethnographic Museum of Turin, to assay the presence of malaria. The results obtained suggest an incidence of malaria of about 40% in the mummies of Gebelen group. Data are compatible with other observations effected on populations living in similar ecological conditions of malarial areas.

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