doi: 10.1093/ajcp/63.2.231.
A rapid, quantitative determination of clottable fibrinogen unaffected by heparin
- PMID: 1115033
- DOI: 10.1093/ajcp/63.2.231
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A rapid, quantitative determination of clottable fibrinogen unaffected by heparin
Am J Clin Pathol.
1975 Feb.
Abstract
A turbidimetric assay for clottable plasma fibrinogen which is not sensitive to heparin or Pyran inhibition is described. The basis of the assay is the substitution of Reptilase-R for the thrombin usually employed. The assay correlates very well with a thrombin turbidimetric method and also has other advantages, including better stability of the clotting enzyme and more rapid attainment of equilibrium.
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