Neurogenic tumors of the mediastinum

Abstract

Neurogenic tumors can arise from neural cells in any location; however, they commonly are found in the mediastinum and, more specifically, most often are located in the posterior compartment. Neurogenic tumors can be benign or malignant, with a wide array of both clinical and pathologic features that are commonly classified by the cell type of origin. These tumors are usually detected on routine chest radiograph, and a computed tomographic scan is required to obtain more information about involvement of local structures. A magnetic resonance imaging scan may be necessary if a dumbbell-shaped component is identified or suspected. Treatment options vary depending on the presentation, but most often surgical resection is recommended. Whereas patients with benign neurogenic tumors have an excellent prognosis with complete surgical resection, patients with malignant neurogenic tumors still have poor long-term survival prospects.