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Review
. 2001 Feb;13(1):109-13.
doi: 10.1016/s0952-7915(00)00190-4.

CD1 and lipid antigens: intracellular pathways for antigen presentation

J Jayawardena-Wolf  1 , A Bendelac
Affiliations
Review

CD1 and lipid antigens: intracellular pathways for antigen presentation

J Jayawardena-Wolf et al. Curr Opin Immunol. 2001 Feb.

Abstract

Recently, different members of the CD1 family of MHC-like molecules have been shown to sample different intracellular compartments to present lipid and glycolipid antigens to T cells. Emerging models suggest that CD1 may have evolved to monitor the integrity of membrane lipids and/or to present microbial lipid antigens to both alpha beta and gamma delta T cells.

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