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. 2000 Nov;38(11):1121-4.
doi: 10.1515/CCLM.2000.168.

External quality assessment of bone metabolism marker assays. initial experiences in a UK NEQAS programme

K M Whitham  1 , A Milford-Ward
Affiliations

External quality assessment of bone metabolism marker assays. initial experiences in a UK NEQAS programme

K M Whitham et al. Clin Chem Lab Med. 2000 Nov.

Abstract

This paper reports on a pilot external quality assessment scheme for bone markers including serum bone alkaline phosphatase and procollagen 1-carboxy terminal propeptide together with urine deoxypyridinoline, N- and C-telopeptides. The data shows poor numerical agreement between commercial assays, between-laboratory imprecision that could be improved, and the need for international standardisation of assays.

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