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Clinical Trial
. 2001 Feb;108(2):254-8.
doi: 10.1016/s0161-6420(00)00514-5.

Primary viscocanalostomy versus trabeculectomy in white patients with open-angle glaucoma: A randomized clinical trial

C Jonescu-Cuypers  1 , P Jacobi, W Konen, G Krieglstein
Affiliations
Clinical Trial

Primary viscocanalostomy versus trabeculectomy in white patients with open-angle glaucoma: A randomized clinical trial

C Jonescu-Cuypers et al. Ophthalmology. 2001 Feb.

Abstract

Purpose: To compare viscocanalostomy, a nonpenetrating procedure for glaucoma treatment, with trabeculectomy.

Design: Randomized controlled trial.

Participants: Twenty white subjects (20 eyes) with open-angle glaucoma with no history of surgery were enrolled.

Methods: Ten subjects were randomly assigned to viscocanalostomy according to Stegmann's technique and 10 subjects to a modified Cairns trabeculectomy. A complete ophthalmologic examination was performed the day before surgery and postoperatively. Further visits were scheduled monthly for 6 to 8 months after surgery.

Main outcome measures: Success was defined as intraocular pressure (IOP) between 7 and 20 mmHg, with no medication.

Results: After a mean follow-up of 6 months (range, 6-8 months), success was obtained in 5 of 10 cases in the trabeculectomy group and in no case in the viscocanalostomy group. With Kaplan-Meier's method, subjects with viscocanalostomy showed shorter postoperative IOP-reduction periods than subjects undergoing trabeculectomy.

Conclusions: According to the results of this short-term study, trabeculectomy was more effective than viscocanalostomy in lowering IOP in glaucomatous eyes of white patients.

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Comment in

  • Viscocanalostomy vs. trabeculectomy.
    Carassa RG, Bettin P, Brancato R. Carassa RG, et al. Ophthalmology. 2002 Mar;109(3):410-1. doi: 10.1016/s0161-6420(01)00979-4. Ophthalmology. 2002. PMID: 11874734 Clinical Trial. No abstract available.
  • Viscocanalostomy vs trabeculetomy.
    Ahmed II, Crandall AS. Ahmed II, et al. Ophthalmology. 2002 Mar;109(3):411-2. doi: 10.1016/s0161-6420(01)00980-0. Ophthalmology. 2002. PMID: 11874735 Clinical Trial. No abstract available.
  • Viscocanalostomy versus trabeculectomy.
    Schuster B. Schuster B. Ophthalmology. 2003 Nov;110(11):2259-60. doi: 10.1016/j.ophtha.2003.08.006. Ophthalmology. 2003. PMID: 14597542 No abstract available.

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