Patterns of physical activity and ultrasound attenuation by heel bone among Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): population based study

Abstract

Objectives: To study associations between patterns of physical activity and ultrasound attenuation by the heel bone in men and women.

Design: Cross sectional, population based study.

Setting: Norfolk.

Participants: 2296 men and 2914 women aged 45-74 registered with general practices participating in European Prospective Investigation into Cancer (EPIC Norfolk).

Results: Self reported time spent in high impact physical activity was strongly and positively associated with ultrasound attenuation by the heel bone, independently of age, weight, and other confounding factors. Men who reported participating in >/=2 hours/week of high impact activity had 8.44 dB/MHz (95% confidence interval 4.49 to 12.40) or 9.5%, higher ultrasound attenuation than men who reported no activity of this type. In women, the difference in ultrasound attenuation between those reporting any high impact activity and those reporting none was 2.41 dB/MHz (0.45 to 4.37) or 3.4% higher. In women this effect was similar in size to that of an age difference of four years. Moderate impact activity had no effect. However, climbing stairs was strongly independently associated with ultrasound attenuation in women (0.64 dB/MHz (0.19 to 1.09) for each additional five flights of stairs). There was a significant negative association in women between time spent watching television or video and heel bone ultrasound attenuation, which decreased by 0.08 dB/MHz (0.02 to 0.14) for each additional hour of viewing a week.

Conclusions: High impact physical activity is independently associated with ultrasound attenuation by the heel bone in men and women. As low ultrasound attenuation has been shown to predict increased risk of hip fracture, interventions to promote participation in high impact activities may help preserve bone density and reduce the risk of fracture. However, in older people such interventions may be inappropriate as they could increase the likelihood of falls.

Figure 1

Self reported physical activity among men and women aged 45-74 in EPIC Norfolk cohort

Figure 2

Mean (SE) ultrasound attenuation according to hours of television and video viewing adjusted for age, weight, smoking history, and ultrasound machine for men and women plus menopausal status and hormone replacement therapy for women

Figure 3

Mean (SE) ultrasound attenuation according to frequency of climbing stairs adjusted for age, weight, smoking history, and ultrasound machine for men and women plus menopausal status and hormone replacement therapy for women