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Review
. 2001 Jan;36(1):21-8.
doi: 10.1016/s0531-5565(00)00205-9.

Prolonged longevity of hypopituitary dwarf mice

A Bartke  1 , H Brown-Borg, J Mattison, B Kinney, S Hauck, C Wright
Affiliations
Review

Prolonged longevity of hypopituitary dwarf mice

A Bartke et al. Exp Gerontol. 2001 Jan.

Abstract

In two types of mutant dwarf mice, congenital deficiencies in pituitary function are associated with remarkably increased life expectancy. In this review, we will describe the key phenotypic characteristics of these animals, the evidence that they exhibit delayed aging, and the mechanisms that are suspected to account for their prolonged longevity.

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