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Review
. 2001 Feb;11(1):13-8.
doi: 10.1016/s0959-437x(00)00150-7.

Cell-cycle-dependent translational control

S Pyronnet  1 , N Sonenberg
Affiliations
Review

Cell-cycle-dependent translational control

S Pyronnet et al. Curr Opin Genet Dev. 2001 Feb.

Abstract

Control of translation in eukaryotes occurs mainly at the initiation step. Translation rates in mammals are robust in the G1 phase of the cell cycle but are low during mitosis. These changes correlate with the activity of several canonical translation initiation factors, which is modulated during the cell cycle to regulate translation.

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