Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001 Jan;26(1):47-54.
doi: 10.1016/s0968-0004(00)01734-5.

Unwinding the 'Gordian knot' of helicase action

P Soultanas  1 , D B Wigley
Affiliations
Review

Unwinding the 'Gordian knot' of helicase action

P Soultanas et al. Trends Biochem Sci. 2001 Jan.

Abstract

Helicases are enzymes involved in every aspect of nucleic acid metabolism. Recent structural and biochemical evidence is beginning to provide details of their molecular mechanism of action. Crystal structures of helicases have revealed an underlying common structural fold. However, although there are many similarities between the mechanisms of different classes of helicase, not all aspects of the helicase activity are the same in all members of this enzyme family.

PubMed Disclaimer

MeSH terms

LinkOut - more resources