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Review
. 2001 Feb;11(2):49-54.
doi: 10.1016/s0962-8924(00)01880-8.

Chromosomal passengers and the (aurora) ABCs of mitosis

R R Adams  1 , M Carmena, W C Earnshaw
Affiliations
Review

Chromosomal passengers and the (aurora) ABCs of mitosis

R R Adams et al. Trends Cell Biol. 2001 Feb.

Abstract

Chromosomal passengers are proteins that move from centromeres to the spindle midzone during mitosis. Recent experiments show that the passengers inner centromere protein (INCENP) and aurora-B kinase are in a macromolecular complex that might also contain a third passenger, survivin. The chromosomal passenger complex functions throughout mitosis in chromosome condensation and segregation, and at the end of mitosis, in the completion of cytokinesis.

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