Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Jan;11(1):137-41.
doi: 10.1128/iai.11.1.137-141.1975.

Immune response to hepatitis B surface antigen

A B Ibrahim, G N Vyas, H A Perkins

Immune response to hepatitis B surface antigen

A B Ibrahim et al. Infect Immun. 1975 Jan.

Abstract

A total of 69 persons were investigated for assessment of cell-mediated and humoral immunity to hepatitis B surface antigen (HBsAg). Three groups, each consisting of 20 normal persons, 20HBsAg carriers, and 20 convalescent hepatitis B patients, were studied for HBsAg, anti-HBs, and leukocyte migration inhibition with purified HBsAg. Sequential sampling if an additional group of nine acute hepatitis B patients defined the cellular and humoral immune response to HBsAg. The antigen was eliminated rapidly by mounting of cell-mediated immune response detectable for a limited period, followed by antibody response in relatively few patients moore than 3 months after clearance of circulating HBsAg.

PubMed Disclaimer

References

    1. JAMA. 1965 Feb 15;191:541-6 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 Jul;60(3):814-21 - PubMed
    1. Lancet. 1972 Oct 21;2(7782):850-3 - PubMed
    1. Clin Exp Immunol. 1973 Sep;15(1):27-34 - PubMed
    1. Am J Med. 1970 Nov;49:669-92 - PubMed

Publication types

Substances

LinkOut - more resources