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Review
. 2001 Mar;90(3):253-69.
doi: 10.1002/1520-6017(200103)90:3<253::aid-jps1>3.0.co;2-w.

Oxidative degradation of pharmaceuticals: theory, mechanisms and inhibition

S Hovorka  1 , C Schöneich
Affiliations
Review

Oxidative degradation of pharmaceuticals: theory, mechanisms and inhibition

S Hovorka et al. J Pharm Sci. 2001 Mar.

Abstract

Oxidation is a common pathway for drug degradation in liquid and solid formulations. The present article reviews mechanistic details of autoxidation and chain oxidation processes, as well as the oxidation of selected functional groups commonly affected in drugs.

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