Ultrasound, antisperm antibody, and hormone profiles after testicular Trucut biopsy

Abstract

Objective: To assess the effect of Trucut needle biopsy on the ultrasound appearances of the testis in obstructive and nonobstructive azoospermia to test serum samples for antisperm antibodies and gonadotropin and testosterone levels.

Design: Prospective case analysis.

Setting: IVF unit.

Patient(s): Sixteen subjects with obstructive azoospermia had postbiopsy ultrasound scans, 18 had assessment of hormone profiles, and 20 had evaluation of antisperm antibodies.

Intervention(s): Trucut needle testicular biopsies under local anesthetic.

Main outcome measure(s): Postbiopsy testicular ultrasound, the presence of serum antisperm antibodies, and follicle stimulating and luteinizing hormone and testosterone levels.

Result(s): There were no postbiopsy hematomas or scars, antisperm antibodies did not develop, and pituitary gonadotropins did not rise nor testosterone levels fall.

Conclusion(s): Trucut needle testicular biopsy in men with obstructive azoospermia is not associated with defects of parenchymal structure or function.