Identification and analysis of eukaryotic promoters: recent computational approaches

Abstract

The DNA sequence of several higher eukaryotes is now complete, and we know the expression patterns of thousands of genes under a variety of conditions. This gives us the opportunity to identify and analyze the parts of a genome believed to be responsible for most transcription control--the promoters. This article gives a short overview of the state-of-the-art techniques for computational promoter localization and analysis, and comments on the most recent advances in the field.