Comment
doi: 10.1038/84743.
Modifying with mitochondria
Affiliations
- PMID: 11175774
- DOI: 10.1038/84743
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Comment
Modifying with mitochondria
Nat Genet.
2001 Feb.
Abstract
An elegant set of mouse crosses has been used to identify a mitochondrial variant that interacts with a nuclear locus on chromosome 10, Ahl, to modify age-related hearing loss. This discovery sets the stage for the identification of factors that modify expression levels and variability of human hearing impairments.
Comment on
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A genetic approach to understanding auditory function.Nat Genet. 2001 Feb;27(2):143-9. doi: 10.1038/84758. Nat Genet. 2001. PMID: 11175778 Review.
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A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice.Nat Genet. 2001 Feb;27(2):191-4. doi: 10.1038/84831. Nat Genet. 2001. PMID: 11175788 Free PMC article.