The complete genome sequence of Vibrio cholerae: a tale of two chromosomes and of two lifestyles
- PMID: 11178241
- PMCID: PMC138858
- DOI: 10.1186/gb-2000-1-3-reviews1016
The complete genome sequence of Vibrio cholerae: a tale of two chromosomes and of two lifestyles
Abstract
Vibrio cholerae O1 has figured prominently in the history of infectious diseases as a cause of periodic global epidemics, an affliction of refugees in areas of social strife and as the disease first subjected to modern epidemiological analysis during the classic investigations of John Snow in mid-19th century London [1]. Thus, publication of the entire genome sequence of V. cholerae O1 (biotype El Tor) in Nature [2] by a consortium of investigators from The Institute for Genomic Research, the University of Maryland and Harvard Medical School is properly regarded as an historic event that will trigger a paradigm shift in the study of this organism.
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Comment in
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Lessons to be learned from studying Vibrio cholerae in model systems.Genome Biol. 2001;2(8):INTERACTIONS1003. doi: 10.1186/gb-2001-2-8-interactions1003. Epub 2001 Jul 31. Genome Biol. 2001. PMID: 11532208 Free PMC article.
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