The function and regulation of vasa-like genes in germ-cell development
- PMID: 11178242
- PMCID: PMC138859
- DOI: 10.1186/gb-2000-1-3-reviews1017
The function and regulation of vasa-like genes in germ-cell development
Abstract
The vasa gene, essential for germ-cell development, was originally identified in Drosophila, and has since been found in other invertebrates and vertebrates. Analysis of these vasa homologs has revealed a highly conserved role for Vasa protein among different organisms, as well as some important differences in its regulation.
Similar articles
-
Vasa homolog genes in mammalian germ cell development.Cell Struct Funct. 2001 Jun;26(3):131-6. doi: 10.1247/csf.26.131. Cell Struct Funct. 2001. PMID: 11565805 Review.
-
A zebrafish vasa morphant abolishes vasa protein but does not affect the establishment of the germline.Genesis. 2001 Jul;30(3):183-5. doi: 10.1002/gene.1060. Genesis. 2001. PMID: 11477703 No abstract available.
-
Germline development in vertebrates and invertebrates.Cell Mol Life Sci. 1999 Jul;55(8-9):1141-63. doi: 10.1007/s000180050363. Cell Mol Life Sci. 1999. PMID: 10442094 Free PMC article. Review.
-
Multiple levels of posttranscriptional control lead to germ line-specific gene expression in the zebrafish.Curr Biol. 2002 Feb 19;12(4):289-94. doi: 10.1016/s0960-9822(02)00679-6. Curr Biol. 2002. PMID: 11864568
-
The human VASA gene is specifically expressed in the germ cell lineage.Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9585-90. doi: 10.1073/pnas.160274797. Proc Natl Acad Sci U S A. 2000. PMID: 10920202 Free PMC article.
Cited by
-
DEAD-Box Helicase 4 (Ddx4)+ Stem Cells Sustain Tumor Progression in Non-Serous Ovarian Cancers.Int J Mol Sci. 2020 Aug 24;21(17):6096. doi: 10.3390/ijms21176096. Int J Mol Sci. 2020. PMID: 32847044 Free PMC article.
-
Transcriptome profiling of testis during sexual maturation stages in Eriocheir sinensis using Illumina sequencing.PLoS One. 2012;7(3):e33735. doi: 10.1371/journal.pone.0033735. Epub 2012 Mar 19. PLoS One. 2012. PMID: 22442720 Free PMC article.
-
Alternative splicing, expression patterns and promoter characters of vasa-like gene from the silkworm, Bombyx mori.Mol Biol Rep. 2012 May;39(5):5967-76. doi: 10.1007/s11033-011-1409-7. Epub 2011 Dec 30. Mol Biol Rep. 2012. PMID: 22207176
-
SpolvlgA is a DDX3/PL10-related DEAD-box RNA helicase expressed in blastomeres and embryonic cells in planarian embryonic development.Int J Biol Sci. 2009;5(1):64-73. doi: 10.7150/ijbs.5.64. Epub 2009 Jan 6. Int J Biol Sci. 2009. PMID: 19159016 Free PMC article.
-
Bombyx Vasa sequesters transposon mRNAs in nuage via phase separation requiring RNA binding and self-association.Nat Commun. 2023 Apr 7;14(1):1942. doi: 10.1038/s41467-023-37634-2. Nat Commun. 2023. PMID: 37029111 Free PMC article.
References
-
- Wylie C. Germ cells. Cell. 1999;96:165–174. - PubMed
-
- Wylie C. Germ cells. Curr Opin Genet Dev. 2000; 10:410–413. - PubMed
-
- Williamson A, Lehmann R. Germ cell development in Drosophila. Annu Rev Cell Dev Biol. 1996;12:365–391. - PubMed
-
- Rongo C, Lehmann R. Regulated synthesis, transport and assembly of the Drosophila germ plasm. Trends Genet. 1996;12:102–109. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases