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. 2000;7(4):370-3.
doi: 10.1007/s005340070031.

Current status and perspectives in clinical islet transplantation

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Current status and perspectives in clinical islet transplantation

R G Bretzel. J Hepatobiliary Pancreat Surg. 2000.

Abstract

Beta-cell replacement, by either pancreas or islet transplantation, is the only treatment to achieve an insulin-independent, constantly normoglycemic state avoiding hypoglycemic episodes in patients with type-1 diabetes mellitus. This article reviews the current state of the worldwide experience based on data provided by the International Islet Transplant Registry; it also illustrates the perspectives of clinical islet transplantation.

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