Seasonal variations in exposure to microbial cell wall components among household waste collectors

Abstract

Background: Collection, separation, and composting of household waste generates organic dusts that may contain the inflammagenic agent endotoxin and (1-->3)-beta-D-glucan, a cell wall component of fungi, plants and certain bacteria. In previous studies, waste collectors have reported a greater number of or more severe symptoms in the summer. To further elucidate whether a seasonal variation in exposure could support previous findings of the presence of symptoms during summer months, a study was performed to assess exposures to airborne (1-->3)-beta-D-glucan and endotoxin during different seasons among household waste collectors handling compostable waste.

Methods: Measurements were made of the amounts of airborne (1-->3)-beta-D-glucan and endotoxin using personal sampler equipment in two household waste collectors handling compostable waste. Measurements were made every second week from September 1998 to January 2000.

Results: The amounts of airborne endotoxin were low during the study period. The amount of airborne (1-->3)-beta-D-glucan was higher during the warm season, and there was a relationship between exposure levels of (1-->3)-beta-D-glucan and outdoor temperature.

Conclusions: The results suggest that household waste collectors handling compostable waste can be exposed to airborne (1-->3)-beta-D-glucan, especially during the warm season, when more symptoms have been reported among waste collectors, according to previous studies. This cannot be interpreted as a causal relationship as household waste may contain several agents that could cause effects. Further studies are needed to explore such relationships.