Cell biology. Stem cells: new excitement, persistent questions
- PMID: 11186385
- DOI: 10.1126/science.290.5497.1672
Cell biology. Stem cells: new excitement, persistent questions
Abstract
On pages 1775 and 1779, independent research teams describe experiments in which bone marrow cells became neuronlike cells in the brain, providing new evidence for the versatility of adult stem cells. But ample uncertainties must be resolved before such results can be translated into therapeutics. The most important next step, say several stem cell researchers, is to identify the molecular processes that underlie the impressive feats of stem cells, as many of the purported breakthroughs are simply observations.
Comment in
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Mutation in embryonic stem cells.Science. 2001 Apr 20;292(5516):438-40. doi: 10.1126/science.292.5516.438b. Science. 2001. PMID: 11330294 No abstract available.
Comment on
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From marrow to brain: expression of neuronal phenotypes in adult mice.Science. 2000 Dec 1;290(5497):1775-9. doi: 10.1126/science.290.5497.1775. Science. 2000. PMID: 11099418
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Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow.Science. 2000 Dec 1;290(5497):1779-82. doi: 10.1126/science.290.5497.1779. Science. 2000. PMID: 11099419
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