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. 1975 Jan-Feb;21(1):95-8.

[Change in the protein spectrum of the erythrocytic membranes in certain anemias]

[Article in Russian]
M V Kamyshentsev, M N Blinov, A S Abdulkadyrova
  • PMID: 1119119

[Change in the protein spectrum of the erythrocytic membranes in certain anemias]

[Article in Russian]
M V Kamyshentsev et al. Vopr Med Khim. 1975 Jan-Feb.

Abstract

Proteins of human erythrocyte membranes were studied in normal state and in different anaemias. After solubilization of cell "shadows" in phenol-urea-acetic acid-water system in membranes there were found, by means of polyacrylamide gel disc electrophoresis, 20 protein fractions with molecular weight from 48000 to 225000; seven of them glycoproteins. In 9 cases out of 36 a complete or partial disappearance of a glycoprotein component with molecular weight of 170000 was observed in erythrocyte membranes from patients with inherited spherocytosis and Markiafava--Mikely disease.

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