Review
doi: 10.1111/j.1749-6632.2000.tb05529.x.
Physiological regulation of uteroglobin/CCSP expression
Affiliations
- PMID: 11193756
- DOI: 10.1111/j.1749-6632.2000.tb05529.x
Item in Clipboard
Review
Physiological regulation of uteroglobin/CCSP expression
Ann N Y Acad Sci.
2000.
Abstract
Uteroglobin/CCSP is expressed specifically in the Clara cells. This allows the gene to be used as a marker to identify the elements regulating the physiologic and cell-specific expression of this gene. The regulation of UG/CCSP by IFN-gamma was shown to be at the level of the proximal promoter by the upregulation of HNF3 beta. This has allowed the determination of the factors responsible for the expression of UG/CCSP.
Similar articles
-
Regulation of the Clara cell secretory protein/uteroglobin promoter in lung.Ann N Y Acad Sci. 2000;923:154-65. doi: 10.1111/j.1749-6632.2000.tb05527.x. Ann N Y Acad Sci. 2000. PMID: 11193754 Review.
-
Pseudomonas aeruginosa and tumor necrosis factor-alpha attenuate Clara cell secretory protein promoter function.Am J Respir Cell Mol Biol. 2002 Feb;26(2):216-23. doi: 10.1165/ajrcmb.26.2.4718. Am J Respir Cell Mol Biol. 2002. PMID: 11804873
-
Cre-mediated recombination in mouse Clara cells.Genesis. 2008 Jun;46(6):300-7. doi: 10.1002/dvg.20396. Genesis. 2008. PMID: 18543320 Free PMC article.
-
Tumor necrosis factor alpha stimulation of human Clara cell secretory protein production by human airway epithelial cells.Ann N Y Acad Sci. 2000;923:193-201. doi: 10.1111/j.1749-6632.2000.tb05530.x. Ann N Y Acad Sci. 2000. PMID: 11193757 Review.
-
Pulmonary phenotype of CCSP/UG deficient mice: a consequence of CCSP deficiency or altered Clara cell function?Ann N Y Acad Sci. 2000;923:202-9. doi: 10.1111/j.1749-6632.2000.tb05531.x. Ann N Y Acad Sci. 2000. PMID: 11193758 Review.
Cited by
-
Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13.J Immunol. 2005 Nov 1;175(9):5708-15. doi: 10.4049/jimmunol.175.9.5708. J Immunol. 2005. PMID: 16237061 Free PMC article.
-
Sexually dimorphic gene expression that overlaps maturation of type II pneumonocytes in fetal mouse lungs.Reprod Biol Endocrinol. 2006 May 4;4:25. doi: 10.1186/1477-7827-4-25. Reprod Biol Endocrinol. 2006. PMID: 16674826 Free PMC article.
-
Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression.J Immunol. 2013 Dec 1;191(11):5460-76. doi: 10.4049/jimmunol.1301576. Epub 2013 Oct 25. J Immunol. 2013. PMID: 24163409 Free PMC article.
-
Sex-dependent regulation of mucin gene transcription and airway secretion and mechanics following intra-airway IL-13 in mice with conditional loss of club cell Creb1.Front Physiol. 2024 Apr 22;15:1392443. doi: 10.3389/fphys.2024.1392443. eCollection 2024. Front Physiol. 2024. PMID: 38711951 Free PMC article.
-
Inactivation of FOXA2 by Respiratory Bacterial Pathogens and Dysregulation of Pulmonary Mucus Homeostasis.Front Immunol. 2020 Mar 25;11:515. doi: 10.3389/fimmu.2020.00515. eCollection 2020. Front Immunol. 2020. PMID: 32269574 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Miscellaneous
